Tuesday , May 7 2024

3D Imaging Could Answer Fundamental Questions About Valley Fever

A Phoenix-based laboratory is capturing detailed images of the fungus that causes valley fever, hoping to better understand how it works. The research could shed light on why the disease spreads at higher rates for Americans of African, Filipino and Mexican descent than others, said Bridget Barker, an assistant professor at Northern Arizona University and the Phoenix-based Translational Genomics Research Institute (TGEN). “Your immune system should find the structures, engulf them and kill them, but we hypothesize that’s not the case for all strains. There might be some strains that survive better and maybe that’s why people get so sick,” Barker said. “The big overarching mystery is why do some people get sick and why don’t others get sick at all?” The fungus coccidioides immitis — or cocci — grows in arid regions of the southwest United States. When swept up by the wind and breathed in, the fungus’ spores can cause valley fever. That sometimes deadly disease infects thousands every
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