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Hundreds of children and their families cycle in and out of UCLA’s Mattel Children’s Hospital each week, and yet Dr. Manish Butte still remembers the day almost two years ago when he met a young boy who could barely walk or talk and needed a feeding tube to eat. “We saw these very large lumps on his forehead, and the lumps were full of fungal infection and they were burrowing through the bones of his skull,” Butte said. Four-year-old Abraham Gonzalez-Martinez was suffering a life-threatening bout of valley fever, a disease caused by inhaling the spores of a fungus that lurks in arid soil in the American Southwest . Also known as coccidioidomycosis or cocci, the fungal disease typically infects the lungs but can spread into other organs, the bones and, in the most severe cases, the brain and nervous system. “He was desperately ill,” Butte said. “He was on multiple antifungal medicines, top doses of everything, and the infection was still spreading.” Today, Abraham is back home with his
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